MIC 201 Lecture Notes - Lecture 16: Membrane Fusion Protein, Orthomyxoviridae, Gp41

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byzantiumtoad203

2 May 2019

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First step: viral attachment protein binds to host receptor: different types of viruses (shapes) have diff attachment proteins. Bacteriophage: have tail fibers, enveloped and nonenveloped: have spike, non enveloped can also have capsid which acts as an attachment. Important to know these receptors to know what kind of host, and to help prevent attachment. Attachment protein is the key and host receptor is the lock receptor. H1 binds to sialic acid receptor on the host, triggers endocytosis encloses into a endosome. In the endosome the low ph exposes fusion peptide the fusion peptide is now anchored at the membrane on the host and allows the virus to be successful. Has a spike protein called gp120 which binds to the receptor cd4. Then it binds to the co receptor on the host and bc of the co receptor, gp41 (fusion peptide) and gp120 gets exposed, and they then attach to the host. Mechanism: membrane fusion fusion peptide (gp41)

Related Questions

1
Which of the following is a component of the HIV virus ?
A
DNA
B
Capsid
C
Nucleus
D
CD4 receptor
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2
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2
What is the function of Reverse Transcriptase?
A
To insert the viral RNA into the host DNA.
B
To make an RNA copy of the viral RNA.
C
To make an RNA copy of the viral DNA.
D
To make a DNA copy of the viral RNA.
E
To insert the viral DNA into the host DNA.
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3
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3
Which of the following stages describes a HIV patient in who has a large number of severe opportunistic infections?
A
Primary HIV infection-lasts for a few weeks
B
Clinically asymptomatic stage-lasts for an average of ten years
C
Symptomatic HIV infection
D
Clinical AIDS
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4
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4
Which of the following individuals should be tested for HIV?
A
A newborn child
B
Alex, who studies excessively
C
Sarah, who takes birth control
D
Joe, who uses intravenous steroids
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5
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5
Harry engaged in risky activity that may have lead to exposure to HIV. Two and a half weeks later, he had an HIV test done and it showed a positive result. Which test most likely was done?
A
CD4 test
B
HIV antibody test
C
PCR test
D
Viral load test
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6
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6
How does an Integrase inhibitor work against the HIV virus?
A
It inhibits the generation of viral DNA from viral RNA.
B
It prevents the entry of HIV into the host cell.
C
It inhibits viral proteins from being inserted into new virus particles.
D
It prevents viral DNA from being inserted into host DNA.
E
It prevents the generation of new viral proteins.
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7
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7
How does a Protease inhibitor work to treat HIV infection?
A
It prevents the release of new viral particles.
B
It cleaves viral proteins interfering with their function.
C
It prevents the cleavage of host DNA preventing viral DNA from being inserted into host DNA.
D
It cleaves Reverse transcriptase preventing the generation of viral DNA.
E
It prevents the binding of gp120 to the CD4 protein.
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8
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8
Which of the following describes a combination therapy for HIV infected persons?
A
A preparation used for stimulating a viral response in the body.
B
A single drug given to HIV infected people since interactions with other medications may promote complications in treatment.
C
A drug cocktail-or-combination of antiviral drugs given to HIV infected people since they can be more effective than when given individually
D
A preparation used for stimulating an immune response in the body.
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9
answerable question reference
For HIV to reproduce, which of the following is most critical?
A
Infecting new subjects
B
Producing a Provirus
C
Entering the host cells
D
Taking over the function of DNA in the cell
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10
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10
HIV is a virus which has the following characteristic?
A
It takes of the RNA of the host cell which subsequently by way of transcription and translation makes new virus
B
It attacks the RNA of the host cell causing cellular death
C
It attacks the DNA of the host cell causing cellular death
D
It takes over the DNA of the host cell which subsequently by way of transcription and translation makes new virus

MIC 201 Lecture Notes - Lecture 16: Membrane Fusion Protein, Orthomyxoviridae, Gp41

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