IPHY 2420 Lecture Notes - Lecture 20: Epigenome, Kidney Stone Disease, Insulin-Like Growth Factor 2
15 Aug 2016
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Document Summary
Epigenetics: practices of one generation can affect following generations: generations. 3rd generation: reproductive cells in fetus: epigenome. Proteins and other molecules that regulate expression of genes: can turn genes on or off . Bioactive food components and gene expression: both together work against disease development. Epigenetics: future generation effects: embryonic development, modifying your epigenome, health implications. Astronaut scott kelly, senator mark kelly (twins, test idea of epigenetics by looking at how twins react to different stressors) Food, smoke, drinks, sun: winter of 1944-45, dutch hunger winter. Food supply blocked by germans as punishment. Dr. tessa roseboom researched effect of extreme malnutrition on women/babies. Now, follow babies born during, before, and after the famine. Fafiane family: mom couldn"t buy milk, so had to breastfeed, but not enough either, daughter started getting kidney stones around. 17, then high blood pressure, breast cancer, raised cholesterol level: sister/brother = few years younger, but no similar health problems.
