MCDB 1150 Lecture Notes - Lecture 4: Rifampicin, Antimicrobial Resistance, Cell Theory

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Unit 1: foundation of modern biological science (cell theory and theory of evolution by natural selection) Suggested reading for unit 1: freeman, chapter 1, sections 1-1. 4, chapter 22, sections 22. 4 (pgs 446- Pp for unit 1: cell theory, theory of evolution by natural selection. Must be variation in heritable traits in population (can"t be a population of clones!) Certain versions of heritable traits (alleles) allow individuals to survive and therefore reproduce in a particular environment. Some individuals in a population will reproduce more frequently in a particular environment. Results in a change in frequency of traits in that population. Frequency: the number of individuals in a population that carry a particular trait (gene, mutation, etc. ) Genes (dna) are copied to rna messages that are translated to protein. Atgccc tcgcat (series of codons, one of which is mutated, changing the shape of the protein, causing the tuberculosis to become antibiotic resistance) Wild type rna polymerase protein binds rifampin and is inhibited.

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