MCDB 1150 Lecture Notes - Lecture 14: Intracellular Parasite, Endoplasmic Reticulum, Integral Membrane Protein
9 Dec 2016
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Document Summary
Bacterial genomes vary in size: resolution of the microscope, bacteria do not have a nucleus, bacteria carry out, eukaryotic cells are much bigger than bacteria. Oxidation of organic fuels to co2 and h2o. Conversion of light energy to chemical energy stored in glucose. Problem for bigger, larger volume cells molecules most diffuse to site of reaction in time. Diffusion allows rapid movement of molecules across very small distances (works for bacteria), so large eukaryotic cells have a hard time. This effectively reduces the volume of the cytosol. Reduces the surface area/volume ratio problem: viruses. Dna, genetic material, protein, can have rna, carbohydrates, use the same genetic code. Rna > dsdna (-) sense is not the coding sequence, (+) sense is basically mrna. What viral genomes would be immediately translatable following injection into the cytoplasm of a host cell: (+) sense rna genome. Fusion of virus envelope with cell membrane - entry into cell.
