BIOLOGY 202L Lecture Notes - Lecture 14: Heterozygote Advantage, Outcrossing, Haplotype

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Decrease in overall fitness of a population as a result of inbreeding and reduction in. **in an inbred population, the homozygous recessive will either be seen excessively or not at all** Increase in genetic disorders due to inbreeding: recessive rare diseases become much more prevalent. Genetic drift: change in the frequency of an allele in a population due to random sampling of organisms ( chance that skews allele frequency) By nature, genetic drift will cause an allele to become either fixed or extinct: the fixed allele becomes dominant and virtually the only allele in existence, the other allele becomes extinct. Population size is not a factor: initial p and q frequencies indicate tendency of allele to become extinct (lower frequency) or fixed (higher frequency) Migration/gene flow: transfer of alleles from gene pool of one population to another. Maintains diversity and variation, preventing divergence within a population.

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