NEUROSCI 277 Lecture Notes - Lecture 3: Hypomania, Deep Brain Stimulation, Selective Serotonin Reuptake Inhibitor
7 Apr 2016
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Externalizing disorders: expressed outwardly towards others and the environment: external or outwardly directed distress. Hyperactivity, impulsivity (core expression of csc activity), aggression (reacting without thinking about consequences) Substance use disorders: addiction: intoxication, craving, tolerance withdrawal. Eating disorders: fearful of gaining wait and abnormal body image. Characterized by at least one: major depressive episode. No history of manic, mixed, or hypo-manic episodes. Major depressive episode: must include either: Anhedonia (key that maps on to the csc to seek enjoyment and reward) Inability to derive pleasure: also include 4 or more of the following. Amygdala hyperactivity is present in depression: trait like activity. Increased amygdala activity in people who are currently depressed and people who are in remission of their depression. Behavioral trait: as the circuit is asked to respond, the hyperactivity manifest as depression. High in trait anxiety (negative affect) are more likely to develop depression when responding to stressors.
