BIOSC-101 Lecture Notes - Lecture 30: Spindle Apparatus, Sister Chromatids, Prophase

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The mitotic cell cycle internal regulators make sure that the [revious [hase has finished before starting a new phase. Interphase extends from the end of one mitosis to the beggining of the next mitosis. Interphase begins as a daughter cell from a previous division cycle enters an intial period of cytoplasmic growht. During this intitial growth stage (g1) the cell makes various rnas, proteins and other cellular molecules but not dna. Then if the cell is going to divvide it enters the s phase (synthesis) and dna is created. Whether a cell divides rapidely or slowly depends on g1. Once start replicationg it takes about 10-12 hours to complete g1, 4-6 hours to complete. After interphase , mitosis proceeds in five stages. During prophase the greatly extended chromosomes that were replicated in interphase begin to condense into compact rodlike structures. While condensation is in progress the nucleolus becomes smaller and eventually dissapears.

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