PSYC 305 Lecture Notes - Lecture 14: Antipsychotic
Document Summary
A person cannot understand that they have a serious psychiatric illness: schizophrenia has never been successfully treated on a large scale by, schizophrenia, alzheimer"s, dementia psychotherapy, major side effects of antipsychotic ( neuroleptics , extrapyramidal syndrome (eps) Tardive dyskinesia (abnormal involuntary movements, particularly: minor side effects: of the mouth and tongue, dry mouth from decreased salivation, lowered blood pressure, atypical drugs, treat core symptoms of schizophrenia without producing eps, have their own side effects, most notably an increased occurrence of diabetes, why do typical antipsychotics cause eps like symptoms, dopamine hypothesis. Supported by pharmacology: all antipsychotic drugs are dopamine receptor antagonists to some degree, psychostimulants increase dopaminergic transmission and, testing of dopamine hypothesis induce a psychotic state. Do schizophrenics have up regulated (more dopamine receptors): no (some labs reported yes) unclear, dopamine hypothesis is making a comeback, schizophrenia is a brain developmental disorder, dr. daniel weinberger, proposed a neurodevelopmental model of schizophrenia.
