BSC 1010 Lecture Notes - Lecture 20: Society Of Jesus, Herman Gorter, Lipid Bilayer
Document Summary
Polar at one end and nonpolar at the other easy to make ex. Polar due to phosphide non polar due to fatty acid chain. The currently accepted model of cell membrane structure, which envisions the membrane as a mosaic of individually inserted protein molecules drifting laterally in a fluid bilayer of phospholipids: gorter and e. grendel. 1925 reasoned that cell membranes must actually be phospholipid bilayers, two molecules thick. 1935 lipid bilayer model coated on both sides with hydrophilic proteins (sandwich model) Proposed that membrane proteins are dispersed, individually inserted into the phospholipid bilayer with their hydrophilic regions protruding. freeze-fracture splits a membrane along the middle of the phospholipid bilayer. When a freeze-fracture preparation is viewed with an electron microscope, protein particles are interspersed in a smooth matrix, supporting the fluid mosaic model. Rarely flip flop from one side to the other. Temperature (as it cools it becomes more solid)
