MCB 3020 Lecture Notes - Lecture 16: Peptidoglycan, Minc, Mine
Document Summary
Reproductive strategies: the reproductive strategies of eukaryotic microbes. Asexual and sexual, haploid or diploid: bacteria and archaea. Haploid only, asexual - binary fission, budding, filamentous. All must replicate and segregate the genome prior to division. Bacterial cell cycle: cell cycle is sequence of events from formation of new cell through the next cell division. Most bacteria divide by binary fission: two pathways function during cycle. Chromosome partitioning: replisome pushes, or condensation of, daughter chromosomes to opposite ends, mreb (murein cluster b) an actin homolog, plays role in determination of cell shape as spiral inside cell periphery, and chromosome segregation. New origins associate with mreb tracks if mreb is mutated, chromosomes do not segregate. Cytokinesis: septation formation of cross walls between daughter cells, several steps. Assembly of z ring linkage of z ring to plasma membrane (cell wall) Z ring formation- role in septation: protein ftsz tubulin homologue, found in most bacteria and archaea.