MCB 3020L Lecture Notes - Lecture 29: Small Interfering Rna, Chemotherapy, Chronic Obstructive Pulmonary Disease
Document Summary
Isolating them from e. coli by making a soup and isolating the product but this can be expensive on an industrial scale. Yeasts and bacillus subtilis continue to secrete therir products. Mammalian cells grown in culture after insertion of recombinant plasmids (used in clinical things) Plant cells can be gorwn in culture, altered and produce products that are large scale and low cost. Consist only of a protein portion of a pathogen, are being made by geneticlly modifying yeasts. Has no change of becoming infected from the vaccine. Usually circular plasmids that include a gene encoding a viral protein under the transcriptional control of a promotr region active in human. May eventually provide cures for some genetic diseases. Possible to remove some cells from a person and transforming them with a nromal gene to replace a defective or mutated genes. Natural process that occurs in a wide variety of organisms and is apparently a defense against viruses and transposons.
