MCB 2000 Lecture Notes - Lecture 2: Helicobacter Pylori, Dental Plaque, Mumps Virus

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Chapter 22: microbial diseases of the gastrointestinal tract. The pathway from the mouth to the anus. Organs involved in grinding food or providing digestive secretions. Components of the gastrointestinal tract digests food absorbs nutrients and water into the blood and eliminates waste. Large intestine (colon)-completes absorption of nutrients: water, steroids and minerals. Oral cavity contains up to 700 different bacterial species. Hcl in stomach; peristalsis and the rapid transport of food helps prevent colonization by microbes. Accumulation of microbes on the surface of the teeth is called dental plaque -biofilm. The plaque is made up of streptococci (streptococcus mutans) and filamentous bacteria. Bacteria hydrolyze the sucrose into glucose and then use glucose to synthesize dextran (gummy polysaccharide) Inside the plaque, bacteria ferment the fructose into lactic acid. Lactic acid damages the enamel of the tooth. Bacteria invade the dentin (calcified tissue of a tooth)

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