ANTH 1001 Lecture Notes - Lecture 9: Tibetan Plateau, Respiratory Rate, Altitude Sickness
Document Summary
Introduction to biological anthropology, week 5, lecture 9__ Individuals who have it- all hemoglobin are shaped differently. And red blood cells turn into a crescent moon sickle shape. Sickle cell build up in capillaries, and reduce blood flow. Genotypes: hba hba (homozygous normal, hbs hbs (homozygous sickle cell variant- sca, hba hbs (heterozygous incomplete dominance sc trait- some sickling occurs in low oxygen situations) Frequency: why does(cid:374)"t (cid:374)atural selectio(cid:374) get rid of sickle cell a(cid:374)e(cid:373)ia. Disease caused by falciparum malaria- from a mosquito: frequency is high where there is malaria. There is selection for heterozygous- resistance to malaria. Geographic distribution and fitness: homozygous normal has reduced fitness, homozygous sca has reduced fitness, heterozygous has increased fitness. Lactase enzyme: breaks up lactose into constituent parts. Glucose and galactose: milk sugar- lactose, most mammals lose the ability to produce lactase after weaning. Adult lactose intolerance- normal way to be mammal: normal lactose digestion.
