BISC 3166 Lecture Notes - Lecture 11: Skeletal Muscle, Troponin, Resting Potential

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27 Feb 2019
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Cardiac muscle- shares some characteristics with skeletal and smooth muscle: striated, highly oxidative removes 70-80% of oxygen in a single pass; therefore, to increase work, must increase flow, excitation- contraction coupling is similar to skeletal muscle. 14-9: basic contractile fibers are not auto-excitable, so the action potential shows a plateau. This means no tetany: unlike normal skeletal muscle, a normal action potential does not release enough ca so all the troponin sites are filled. Some factors (like epi) can increase the amount of ca released and increase the force of contraction. Fibers are joined at ends in intercalated discs having. Gap junctions that form 2 syncitia atrial and ventricular. Some cardiac muscle cells are modified to form an excitatory and conduction system. Purkinje cells are auto-excitable but depolarize very slowly nodes and bundles are faster the fastest to depolarize are in the sa node - pacemaker.

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