BIOL 1414 Lecture Notes - Lecture 28: Antigen, Cytomegalovirus Retinitis, Indinavir
Document Summary
Chapter - human immunodeficiency virus that causes acquired immunodeficiency. Genetic mutations that disable the immune response. Before antibiotics those individuals died as infants when their maternally transmitted antibodies ran out. Cancer and chemotherapy this is very hard on the immune system. Malnutrition - remember that the ir depends upon the generation of millions of cells, so lack of protein in the diet would prevent an ir. In 1978, it was discovered that a particular infection could induce or cause immunodeficiency. This is acquired that is not present at birth not congenital. Its genome is two segments of identical pieces of rna. It has a cone like capsid surrounded by a lipid envelope. P27 - main capsid protein (makes up the capsomeres) Gp41 - holds the head on the peplomer. Gp120 - is the head on the peplomer. This is responsible for attachment to the cells. Reverse transcriptase enzyme that converts the rna genome into dna.
