PSY-B - Psychology PSY-B 320 Lecture Notes - Lecture 19: Epidermal Growth Factor, Gliogenesis, Synaptic Pruning
21 Feb 2017
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Cell birth/cell differentiation (neurogenesis; gliogenesis: a chemical compound (neurotrophic factor) acts to support growth, differentiation and survival in developing neurons; begins about 7 weeks after conception. The brain can more easily cope with injury during this time (first 5 months of gestation when primarily neurogenesis is taking place: neurogenesis is largely complete by 5 months (exception: hippocampus makes new cells throughout life) Cell migration: begins shortly after first neurons are generated, continues for 6 weeks in cortex and longer in hippocampus, damage has more serious consequences than during neurogenesis. Radial glial cell: path-making cell that a migrating neuron follows to its appropriate destination. Cell differentiation: neuroblasts become specific types of neurons, begins after cells have begun to migrate, essentially complete at birth. Although neuron maturation, which includes the growth of dendrites, axons, and synapses, goes on for years and, in some parts of the brain, may continue throughout adulthood.
