ECON 1 Lecture Notes - Lecture 2: Chromosome, Fucose, Reagent
Document Summary
Blood group antigens: an inherited character of rbc surface detectable by specific alloantibody, may be a glycoprotein, or glycolipid, or protein, clinically important in transfusion and transplantation, blood group antigens may function as: Transporters, receptors, anchors of red cell cytoskeleton, Regulators of autologous complement to prevent rbc destruction, Providers of extracellular carbohydrate matrix to protect the cell from mechanical damage. Blood group system: these are classified into 30 blood group systems, each blood group system represents a genetically discrete entity. The abo blood group determination is dependent on the inheritance of genes that code for proteins for the non-combination or combination of either of the enzymes for the synthesis of specific blood group antigen types. Abo blood group antigens present on red blood cells (natural antigens) This a type of blood group which is formed due to the non-inheritance of all the blood antigens. The specific blood group antigen affected is the h substance.
