BISC 310 Lecture Notes - Lecture 6: Nuclear Pore, Start Codon, Phenylalanine

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scarletsheep32

2 Nov 2016

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A surprisingly small amount of dna is coding specifically for making a protein, a lot of the dna is related somehow to the process of protein synthesis. Flow of genetic information in cell: central dogma of molecular biology: Translation: most, not all, transcription occurs in the nucleus, and translation in the cytosol. G c: have different sugar and have uracil rather than thymine, rna polymerase reads dna and makes complementary rna strand, rna synthesized in 5" to 3" direction (same direction as. = 16: if nucleotides read 3 at a time, 4 bases (agcu) could code for 64 amino acids (43. If it already has a metabolic function, it is a protein, too, but some need modification before it is a protein. After translation: polypeptides may have sugars, lipids, etc. added before becoming functional proteins, proteins with multiple polypeptides must be assembled into functional proteins, all modifications to polypeptides following translation are: post-translational modifications.

Related Questions

QUESTION 1

The RNA recognition motif is the most common RNA-binding domain in hnRNP proteins. Another name for this motif is:

A) all are correct

B) RNA-binding domain

C) KH motif

D) RNA motif

QUESTION 2

In an experiment you have used recombinant DNA technology to create hnRNP C protein tagged with green fluorescent protein and hnRNP A1 protein tagged with red fluorescent protein. What would you expect to see when the proteins are expressed and visualized in Xenopus cells?

A) red fluorescence only in the nucleus

B) green fluorescence only in the cytoplasm

C) red fluorescence only in the cytoplasm

D) green and red fluorescence in the nucleus

QUESTION 3

Mutations that affect the binding of an SR protein to an exonic splicing enhancer can cause exon skipping in some genes, producing mRNAs that when translated yield nonfunctional proteins. In addition to an RNA-binding domain, SR proteins also contain an RS domain that is involved in binding:

A) none of the above

B) RNA

C) protein

D) DNA

burgundyyellowjacket390

Answer the following True or False questions and briefly explain your answers.

True or False EXPLAIN: Most human cells, in a single individual, contain the same amount and type of DNA

True or False EXPLAIN: Most human cells, in a single individual, contain the same amount and type of protein.

True or False EXPLAIN: Once a gene is transcribed, it is always translated immediately.

True or False EXPLAIN: RNA polymerase binds to the promoters of all genes at all times, so that it is prepared for transcription.

True or False EXPLAIN: Some transcription factors are general (they play a role in the transcription of most or all genes), while other transcription factors are specific to just a few genes.

True or False: EXPLAIN Turning genes on at the right time and place requires both specific regulatory DNA sequences and specific regulatory proteins.

Which of the following statements is true?

A.) Molecules of mRNA are translated from 3' to 5'

B.) For each amino acid found naturally in proteins, there is only one codon in the genetic code.

C.)The Shine-Dalgarno sequence is found in the promoters of genes in both prokaryotic and eukaryotic organisms.

D.) During translation, both strands of DNA are used as templates for the construction of two new strands of protein.

E.) When considering the initiation of transcription one often finds consensus sequences, such as the TATA box, located in the region of the DNA where RNA polymerase(s) bind.

BISC 310 Lecture Notes - Lecture 6: Nuclear Pore, Start Codon, Phenylalanine

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