BIOL 1011 Lecture : Lecture5
Document Summary
Dna structure: four nucleotides, complementary base pairing (hydrogen bonds, double helix two backbones, twisted around each other, anti-parallel backbones. Rna is made of a single backbone: dna made of double backbone, hydrogen bonds holding it together, structure winds around itself and forms double helix. Biology 1201 kns: mechanism is called semi-conservative, keeps one old strand and has one new one, dna replication, begins at many origins, strands must separate and unwind. 3" end: the primer builds 5" to 3" and it is anti-parallel, with the primer, directionality is very important, add primer, in order to start this process you have to prime it. Biology 1201 kns: replication, fuse sections, dna ligase. Biology 1201 kns: it really looks like this: (figure 16. 18) Overview of dna replication: strands separate and unwind, helicase, topoisomerases, and ssb proteins, add primer, primase, replication. Biology 1201 kns: dna polymerase, fuse sections/fragments, dna ligase, new sections built 5" to 3" end and anti-parallel always.
