C_S_D 4430 Lecture Notes - Lecture 42: Neural Tube, Neural Tube Defect, Neural Groove
Document Summary
A blastocyst is made up of embryonic cells (blastomeres) that surround a central cavity (the blastocoel) The blastomeres begin to move and reorganize creating folds within the blastocyst. This folding results in the formation of 3 germ layers: Ectoderm (outer layer) cells of this layer give rise to nervous system, the sensory systems, and skin and hair. Mesoderm (middle layer) cells of this layer give rise to muscles, skeleton, connective tissue, and cardiovascular and urogenital system. Endoderm (inner layer) cells of this layer give rise to digestive system and other internal organs. Cell layers along the midline of the ectoderm thicken to form the neural plate, the neural plate is broadcast at the end that will become the head of the developing embryo. A groove forms down the center of the neural plate. This is referred to as the neural groove.
