MB 351 Lecture 73: 16.5 Indirect Disease Types
Document Summary
16. 5 indirect disease types: animal transmission, origin in non-human vertebrates. Zoonosis: animal disease transf from animal to human, direct contact, bites, aerosols, can be prevented by veterinary or immunizations, ex: rabies. In wild animals such as ones that live in forest. Sometimes domestic animals: rhabdovirus, affects cns of warm blooded animals, bite from infected animal transf thru saliva, mult at origin and moves to cns. Fever, excitation, and anxiety develops: death by resp paralysis, preventable by vaccine, enzootic, endemic in certain populations due to inadequate vaccinations, ex: hantavirus, enveloped. Inhalation of rodent excretions: humans are incidental hosts, ex: plague, y. pestis, gram neg, encapsulated rod, white and flat colonies, use fleas to transfer to rats when give to other mammals, humans are incidental if encounter rat, virulence factors. Lethal exotoxins: endotoxins, accumulate in lymph nodes. Forms: bubonic, go to lymph nodes and replicate.
