BIOS 350 Lecture Notes - Lecture 30: Rickettsia Prowazekii, Human Monocytotropic Ehrlichiosis, Headache

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Vectorborne and soilborne bacterial and viral diseases: animal-transmitted viral diseases. Zoonosis: animal disease transmissible to humans, generally transmitted via direct contact, aerosols, or bites, diseases in animals may be either: Rabies: occurs primarily as an epizootic disease in animals but can be spread as a zoonotic disease to humans (figure 30. 1) Reservoirs in the united states are raccoons, skunks, coyotes, foxes, and bats: over 50,000 people die annually, primarily in developing countries, over 1 million people receive postexposure prophylactic care each year. Rhabdovirus: a negative-strand rna virus that causes rabies. Enters the body through a wound or bite. In humans, 9 months may pass before onset of symptoms. Virus proliferates in the brain and leads to fever, excitation, dilation of the pupils, excessive salivation, anxiety, and fear of swallowing. Rabies is diagnosed using tissue samples (figure 30. 2) Victim can be passively immunized with rabies immune globulin: a rabies virus vaccine also provides immunization.