BIOS10115 Lecture Notes - Lecture 6: Helminths, Eukaryote, Mycosis
16 Oct 2016
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Virus review: not a cell, no cell membrane, nucleus, organelles, cytoplasm, obligate intracellular parasite. Can only replicate within a living cell: contain either dna/rna surrounded by protein capsid, naked vs. enveloped, can"t see with lm, need em. Steps of viral replication: adsorption attach/absorbed into host cell wall, penetration penetrates cell wall, dna injected, synthesis duplicate genetic material. Uses bacterial machinery to make mass quantities of themselves (if lytic: maturation, release leaves cell to infect another. Bacteriophage can be lytic: disrupt bacterial chromosome, reproduce in great numbers, break out of cell. Bacteriophage as drugs: do not harm humans, specific to what type of cell they can infect (bacteria, have been used to treat patients with antibiotic resistant infections (don"t respond to antibiotics) Few side effects (but still being tested in us) The lysogenic cycle: lysogeny= when a virus does not lyse the cell. Virus becomes part of host cell genome called a prophage/provirus.
