BIO 203 Lecture Notes - Lecture 17: Cancer, Dysplasia, Angiogenesis

12 views3 pages
Uncontrolled cell division
Development of cancer
Multiple mutations
Cancer and epigenomics
Reducing the risk of cancer
Uncontrolled cell division
All forms of cancer share one characteristic: uncontrolled cell division
One in three people in the US will develop cancer
Tumor (neoplasm)=a new and abnormal growth of cells
Two basic types
Benign tumors
Abnormal mass of tissue surrounded by a capsule of connective
Usually remains at the site where it forms
Often can be removed completely by surgery
Malignant tumor
Invades surrounding tissue
Spreads to multiple locations=metastsis
Stages of cancer development
Dysplasia in tissues of precancerous cells
Carcinoma in situ
Development of blood vessels-angiogenesis
1. Dysplasia
Precancerous cells look different from normal cells
Abnormal shape caused by ragged edges
Unusually large nuclei with odd shape
May have extra chromosomes or be missing parts of some chromosomes
Form a disorganized clump
2. Carcinoma in situ (“cancer in place”)
Tiny mass only a millimeter or two in diameter
3. Tumor attracts a blood supply- angiogenesis
Blood brings nutrients and carries away wastes, allowing continued growth
Vessels form an escape route for tumor cells
Unlock document

This preview shows page 1 of the document.
Unlock all 3 pages and 3 million more documents.

Already have an account? Log in

Get OneClass Notes+

Unlimited access to class notes and textbook notes.

YearlyBest Value
75% OFF
$8 USD/m
$30 USD/m
You will be charged $96 USD upfront and auto renewed at the end of each cycle. You may cancel anytime under Payment Settings. For more information, see our Terms and Privacy.
Payments are encrypted using 256-bit SSL. Powered by Stripe.