NURS 282 Lecture Notes - Lecture 2: Itraconazole, Indigestion, Spironolactone
Document Summary
Initiated w/ sexual arousal: parasympathetic signaling penis. Revatio : use in ed, dm, spinal cord injuries, transurethral prostate resection, physical etiology unknown, effect in healthy men ~ placebo, females, kinetics, high fat meal ~ bioavailability, 1h peak conc. 2h: cyp-3a4 metabolism, no grapefruit juice, renal elimination, doa ~ 2-4h, ade, hypotension, caution w/ alpha blockers. If they have bph: priapism, erection > 4h, common, need to go to the emergency room, ha, flushing, dyspepsia. Nasal congestion, diarrhea, rash, dizziness: transient vision disturbances, mild, naion, rare. Nasal congestion, diarrhea, rash, dizziness: transient vision disturbances, mild, nitrates (shouldn"t be used with the pde5 inhibitors, concurrent use ci, dual cgmp. Patho of priapism: painful erection lasting longer >4-6h, result of stimulation, common in 5-10yo & 20-50yo, types, blood in corpus cavernosum, non-ischemic, high-flow, blood trapped w/in penis. Illicit drug use ~ cocaine, ecstasy, marijuana: requires medical attention immediately, no tx = penile tissue damage, >24h ~ permeant inability to perform, complications.
