BIOL 039 Lecture Notes - Lecture 14: Moe Williams, Mendelian Inheritance, Genetic Heterogeneity
Document Summary
Mating of two organisms with similar mutant phenotypes can lead to wild type offspring. Complementation occurs when the mutations in the parents affect different genes. Mutation in different genes can produce the same or very similar mutant phenotypes. When two pure breeding organisms with similar mutant phenotypes are mated. If complementation occurs, wild type offspring are obtained and the mutations are known to affect two different genes. When the mutations fail to complement, the offspring have the mutant phenotype and the mutations are known to affect the same gene. Mutation that mutually fail to complement one another are called a complementation group (gene) Genetic linkage can be quantified to map the positions of genes on chrom. Comparing observed frequencies of gametes or progeny phenotypes with those expected under independent assorted. If genes are linked, parental allele combinations will be observed at higher frequency than predicted by chance.
