B M B 211 Lecture Notes - Lecture 6: Mitosis, Cell Membrane, Tubulin
30 Sep 2016
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Document Summary
Every protein with a unique three dimensional structure can perform a unique function. Fibrous proteins are an abundant group whose primary role is structures. In many cells, a network of actin filaments supports the plasma membrane. Quaternary structure is needed ( and come together) There is a positive end and a negative end, tubulin can grow from each side but the positive end has faster polymerization. Compounds that interfere with microtubule dynamics can have drastic physiological effects (depolymerization, gets stuck in mitosis which leads to cancerous tumors) Myoglobin (in muscle) and hemoglobin (in blood) are globular proteins with the function of transporting oxygen. Hemoglobin has four heme groups and myoglobin has one (myoglobin can bind one oxygen) Without heme, myoglobin and hemoglobin wouldn"t be able to bind the oxygen. Histines protect iron from getting oxidized (oxidized iron cannot bind oxygen)
