BIOSC 0150 Lecture Notes - Lecture 14: Golgi Apparatus, Endosome, Nuclear Membrane

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Our tour through a typical animal cell: we talked about. Ribosomes: lysosomes, smooth er, cytoskeleton (next class) Lysosomes are the cell"s recycling center: proteasome = garbage can. Destroys misfolded proteins: lysosome = recycling. Breaks down things to reuse them: uses acid hydrolases (enzymes) Things come in, are hydrolyzed and sent out to be used for different things: an acidized compartment (look at recording) Has a ph of 5. 0 in the middle. If it were to burst open, the enzymes inside would not work. Aka, they can only work in the lysosome. In order to maintain ph, the proton pumps pump in h+ molecules: destroys macromolecules that are already in the cytoplasm. Macromolecules that enter the cell via receptor-mediated endocytosis can be digested in lysosomes: macromolecules bind to receptors, endocytic vesicle forms, reverse of exocytosis. Brings material from the exterior to the interior: proteins, carbs, & lipids go in.

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