BIOL 12100 Lecture Notes - Lecture 20: Antibody, Encephalitis, Retrovirus
Document Summary
Virus factory hiv assembles virus bud off. White blood cells t helper cells virus cd4 membrane protein. T helper cells(cd4 cells) are important to immune system. Cd4 cells dies, virus concentration goes up. Not killed directly by hiv but opportunistic infections (oi) Low cd4 cells count 200 or less/mm^3 (normal cd count 500-1500) Flu-like symptoms (fever, rash , swollen glands) Inactive state where there are no symptoms. Rt does not copy accurately (mutates at a high rate compared to others) Drug resistance - many new hiv mutants. Chance resistant to drug a is 1/100000. Chance resistant to drug b is 1/100000. Chance resistant to both drug is 1/10^10. Prevent hiv from attacking to healthy cd4 cells. Block enzyme that inserts viral dna into host genome. Mostly male homosexuals, iv drug or both. 1 in 6 (16%) undiagnosed(don"t know about it) 2. 1 million have hiv new infection (2013) Male = female in prevalence (percentage that have hiv)