11:115:301 Lecture Notes - Lecture 11: Acetyl-Coa, Energy Carrier, Good Energy
22 Sep 2019
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Intermediary metabolism: conversion of environmental energy (carbohydrates + fats, sunlight) cellular energy currency atp. Atp then used in conjunction with building blocks to construct macromolecules of the cell. Cell can do this with a limited number of basic reaction mechanisms (6) Metabolic pathways are linked by the energy carrier atp. Glucose (6c) 3c lactic acid or acetyl coa. Anabolic pathways use that energy to synthesize new molecules. Anaerobic process predate the formation of o2 in the environment. Atp has 2 high energy anhydride bonds. Atp = energy currency of the cell. What makes a molecule a good energy carrier. Much less energy the adp or atp. Phosphate connected by ester bond = -2. 2 kcal/mol. Phosphate-phosphate anhydride bond in atp = -7. 3 kcal/mol. Free energy of atp > adp + pi. Charge repulsion when the phosphates are put together ( h) The more resonance forms there are the higher the entropy. Two molecules instead of just atp ( s)
