01:119:115 Lecture Notes - Lecture 20: G. H. Hardy, Wilhelm Weinberg, Allele Frequency

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Evolution: change in populations over generations, not change in individuals over lifetime. Natural selection acts on individuals, but only populations evolve. Microevolution: minor evolutionary changes of populations/change in the allele frequencies in populations over generations. Genetic variations are necessary for evolution to occur. Phenotype = product of inherited genotype + environmental influences. Determined by a single gene ex: mendel"s pea plant characters. Only genetically determined part of phenotype variation can affect evolution. Natural selection can only act on variation with a genetic component. Some phenotypic differences either-or basis : other phenotypic differences vary in gradation , sources of genetic variation. Three mechanisms cause allele frequency change: natural selection - survival of the fittest, genetic drift - bottleneck/founder effect, gene flow - migration. Determined by 2 or more genes ex: height in humans: genetic variations. Variation differs among individuals in genes or nucleotide sequence. Can be measured as gene variability or as nucleotide variability.

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