01:119:115 Lecture Notes - Lecture 6: Homeostasis, Pertussis, Blood Vessel

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Regulation: cells need to control cellular processes. Environmental stimuli: cells need to be able to respond to signals from their environment (example: feedback loops) Used when there are no distance between cells; direct contact. Examples include plant cells (gap junctions) and white blood cells and their helper t cells. Used when there is a small distance between cells. Examples are nerve cells (synapses are the gaps between the cells: endocrine (long distance) signaling. Examples are hormones traveling thru the blood (pituitary gland in brain sends out hormones that are sent in the bloodstream to areas of body) Stages of cell signaling: reception (receiving the signal, transduction (passing on the signal, usually to the nucleus, response (cellular changes because of the signal) The actual chemical signals traveling from cell to cell. Too large and polar to travel through the lipid bilayer. Called ligands; a smaller molecule that binds to a larger one.

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