01:119:116 Lecture 12: Lecture 12

• School: Rutgers University
• Department: Biological Science
• Course: 01:119:116
• Professor: Gregory Transue

Document Summary

Endocrine system: intercellular communication, introduction to hormones. Travels through body bathing all cells->binds to a target cell. Target cell = any cell that has a receptor for the hormone. Receptor cell: has large glycoproteins/proteins on surface of cell. Cells receive too low signal= receptor-up: types of intercellular communication. Types of communication are classified into 5 paths. Endocrine, paracrine (only to 2 or 3 cells nearby; short-distance), autocrine, synaptic, neuroendocrine. Amines: from a single amino acid; ex: epinephrine. Pheromones: chemicals released from body to communicate with someone else. Functions: define territory; warning of predators; attraction of mates. Water soluble uses: signal transduction (takes signal from outside and brings it into the cell) Binds to membrane receptor coupled with a g protein. When hormones binds with receptor the g protein activates (changes shape) They do this by adding a phosphate group to a specific protein. Activates many types of protein kinases (enzymes in the cells)