01:119:116 Lecture Notes - Lecture 19: Polyspermy, Axon Hillock, Membrane Potential

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Conduct messages as electrical signals and integrate information. A neuron is: cell body-contains all organelles: neuron anatomy. Axon: transmits neural impulse away from cell body to: Usually just one long axon > 1m in a giraffe. End of axon divides (usually) into many branches. Nerve=axons of many neurons, held together with connective tissues. Result is that there is a difference in % ions inside (cytosol) and outside (extra- cellular fluid) of a membrane. Only excitable cells can rapidly generate changes in membrane potential. Resting potential (rp) between -60 and -80 mv. -70mv = maintained by the sodium-potassium pump & ion channels. Sodium-potassium pump 3na+ out, 2 k+ into cell. Each pump requires atp to pump against the gradient. Ion channels-ions defuse across membrane as they move, they carry an electrical charge. Any net movement of + or generates membrane potential (the possibility of doing some work) The membrane is 100x more permeable to k+ than na+

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