01:146:295 Lecture Notes - Lecture 7: Otto Loewi, Neuromuscular Junction, Gap Junction

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Synaptic transmission and vesicle transport 9/25/18: they are two types of synapse, chemical and electrical. Most synapses in the vertebrate"s nervous system are chemical synapses (neurotransmitters are released from chemical synapse): electrical synapse they occur at a site called a gap junction. Where two membranes of two nerve cells meet (could be two cell bodies). They are bidirectional that is, they can move in both directions. They can occur very quickly, voltage between cells are transferred in sync. The cell membrane of the cells are in really close proximately. The gap junctions are made up of 2 connexon and each connexon are made up of 6 connexin (joined together forming a hollow tube). The channels line up connecting the membrane of two cells. Small ions and second messengers can be transported through the gap junction. The space in between the post synaptic and presynaptic neuron is known as the synaptic cleft. the post synaptic side is called the density.

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