01:830:310 Lecture Notes - Lecture 10: Positron Emission Tomography, Ct Scan, Diffusion Mri
30 Jul 2016
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Document Summary
Determination of the structure and morphology of tissue. Need to stain tissue in order to be able to see cells. Golgi stains - using silver chromate on brain tissue stains some neurons all black. Nissl stains - dyes only and all cell bodies; allows you to count cells and see organelles. Drew picture of neurons with golgi stains. Discrimination of low and high density regions in the body. High density areas (ex. bone) seen as white on x-ray film. Disadvantage: poor discrimination between brain tissue and csf. Advantages: picks up tumors, skull fractures and hemorrhage, cheap, easily available. Disadvantages: only 2-dimensional images, poor structural resolution (i. e. brain regions difficult to discern), cumulative radiation. Catheter inserted via an external artery (ex. femoral artery) and guided close to the site of entry of arterial supply of the brain (ex. internal carotid) Vascular shifting due to lesions or degeneration of brain tissue.
