01:830:331 Lecture Notes - Lecture 44: Medial Geniculate Nucleus, Classical Conditioning, Fear Conditioning

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~hebb rule explains how neurons can be changed by experience. ~says that if a synapse repeatedly becomes active at the same that the postsynaptic neuron fires, the synapse will be structurally/chemically strengthened. ~the synaptic connection between the conditioned stimulus and the behavioral response is strengthened, which makes it become an important stimulus. ~hebb"s model for acquisition of associations basically the same thing. Took rats home and put them in stimulating environment, they became smarter. ~strengthening of synaptic connections can happen artificially by electrical stimulation. ~the us (unconditioned stimulus) is a mild foot-shock. ~the ur (unconditioned response) is reflexive freezing behavior, sympathetic arousal. ~the cs (conditioned stimulus) is a tone sound. ~the cr (conditioned response) becomes the freezing behavior. ~rat with an amygdala lesion would not be able to be conditioned and thus wouldn"t have. ~note: auditory part of the thalamus is the mgn (medial geniculate nucleus) ~connection from extralemniscal (in mgn) to lateral nucleus (in amygdala) is very fast.

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