NURS 3360 Lecture Notes - Lecture 1: Threshold Of Pain, Pain Tolerance, Neuropathic Pain

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2: pain at one location may cause an increase in the threshold in another location. An individual with many painful sites may report only the most painful. After the dominant pain is diminished, the individual may then identify other painful areas: duration of time or the intensity of pain that a person will endure before initiating pain responses. Nociception: special receptors that respond only to noxious stimuli and generate nerve. 4 impulses which the brain interprets as pain. 5: conversion of a stimulus to an action potential at the site of tissue injury, chemical substances are released with cellular damage i. e. histamine (potent vasodilator), serotonin (happy neurotransmitter), and prostaglandins (substance that controls pain interpretation). Ibuprofen blocks prostaglandins: chemicals sensitize the primary afferent nociceptors that carry painful stimuli, some analgesics work by interfering in the production of these chemicals i. e. nsaids.

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