BIO 103 Lecture Notes - Lecture 6: Huntingtin, Valine, Hemoglobin
9 Oct 2017
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Document Summary
Mutation must be present in the gametes (spermatocyte or oocyte) in order to be passed down to offspring. Mitochondria has its own set of dna. Sperm only contributes; the egg contributes everything else (including all the organelles) if mom has damaged mitochondria all children will have the damage. Polymorphism many shapes/forms of the same gene: diff in base seq of dna samples, polymorphism =! Allele: different dna sequence for the same protein. How similar is one person"s dna to another person"s dna: 99. 5 99. 9% Large percentage of dna is non-coding == not a gene changes to this dna doesn"t matter (or so we think) Mutation can occur but not cause a change in protein sequence. Some mutations cause a change in a trait that isn"t harmful (blue eyes vs brown eyes) Mutations aren"t always bad: can cause positive changes advantages evolution. Huntington"s disease example of disease due to repeated sequence (insertions) mutation.
