BIO 315 Lecture Notes - Lecture 10: Propionibacterium Acnes, Xeroderma, Body Odor
23 Jan 2020
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Staphylococci: micrococci, areas with moisture have higher populations, metabolize sweat and contribute to body odor, gram-positive pleomorphic rods (diphtheroids) Propionibacterium acnes inhabits hair follicles; anaerobic: produce acids that maintain low skin ph. Corynebacterium xerosis occupy the skin surface; aerobic: yeast, malassezia furfur; causes dandruff, microbial diseases of the skin, vesicles: small, fluid-filled lesions, bullae: vesicles larger than 1 cm in diameter. Spherical gram-positive bacteria; from irregular clusters: many produce coagulase, enzyme that clots fibrin in the blood, used to identify types of staphylococci, staphylococcus epidermidis. Carried in the nasal passages of 20% of the population. Golden-yellow colonies: may produce damaging toxins and cause sepsis. Avoids host defenses in the skin: secretes proteins and toxins that kill phagocytic cells, humans possess antibodies against s. aureus, mrsa strains are antibiotic-resistant, scalded skin syndrome. Toxin b causes exfoliation: toxic shock syndrome (tss) Fever, vomiting, shock, and organ failure caused by toxic shock syndrome toxin.
