BIOL 111 Lecture Notes - Lecture 14: Gtpase, Cytochrome C, Sildenafil
Document Summary
Transduction: multistep pathway; several molecules involved, activation of proteins (addition/removal of phosphate groups); release other small molecules as messengers; etc, g r e at amplifying signal = benefit, more opportunities for coordination control = allows regulation of response. S ignal transduction p athways: triggers first step in the chain of molecular interactions -, r elay molecules: relay a signal from receptor to response particular response. P rotein interaction = unifying theme for all cellular activities! S ignaling molecule is not physically passed along; most of the time never enters cell. S ignal is transduced into diff form at eat step (shape change in protein) P rotein p hosphorylation and dephosphorylation: a common cause of shape change. Calcium signaling: unstimulated cells maintain low c a 2+ in the cytosol by actively pumping it out. S timulation causes a rapid influx of c a 2+ into the cytosol. E xample of active transport! (since it"s pumping from low to high;