BIOL 111 Lecture Notes - Lecture 8: Activation Energy, Endergonic Reaction, Phosphorylation
31 Jul 2016
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Document Summary
Energy coupling use of exergonic process to drive an endergonic one. Bonds between phosphate groups of atp can be broken by hydrolysis releasing a phosphate group is somewhat greater than the energy most other molecules could deliver. Phosphorylation- transfer of a phosphate group from atp to some other molecules, such as the reactant-> recipient molecule = phosphorylated. Intermediate is more reactive than the original unphosphylated molecules. Phosphorylation and dephosphorylation promote crucial protein shape changes during many other important cellular processes as well. Enzyme- macromolecule that acts as a catalyst, a chemical agent that speeds up a reaction without being consumed by the reaction. Activation energy- amount of energy needed to push the reactant in a unstable condition (transition state) Proteins, dna, and other complex cellular molecules are rich in free energy-> have potential to decompose spontaneously. Enzymes- react with speci c substrates-> form enzyme substrate complex-> creates products.
