NRSC 335 Lecture Notes - Lecture 9: Myasthenia Gravis, Monoamine Oxidase, Substantia Nigra

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E . x. monoamine oxidase: r euptake by presynaptic neuron recycled, auto receptors. Inhibit release: negative feedback channels, after synapse, types. Psychopharmacology: neurotransmitters, dozens, but 3-4 major classes, acetylcholine (ach) Found in the periphery: at the neuromuscular junctions. P eripheral motor neurons: nmj, myasthenia gravis. P arasympathetic division: decreases heart rate, brain: nucleus basalis of meynert, memory, attention, alzheimer"s, monoamines, catecholamine. C ortical desynchronization: dopamine (da) and norepinephrine (ne, motivation, reward, attention, dopamine. S ubstantia nigra -> mid brain: brain, r eward systems, drugs, food, sex, movement, too little da - S end ne to the rest of the brain: disorder, amino acids, g oogle this, serotonin (5-hydroxytryptophan) (5-ht) S leep/wake cycle: glutamate (glu) and gamma-amino- butyric acid (gaba, brain"s on and off systems, g lutamate, major excitatory transmitter in brain, brain: e ntir e brain. S troke, epilepsy, toxins: r ed tide, algal blooms.

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