VTPB 221 Lecture Notes - Lecture 1: Rift Valley Fever, Viral Hemorrhagic Fever, Encephalitis

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The jungle fights back hemorrhagic viral diseases part 3. 3rd disease caused by flavivirus=west nile virus. Wnv: mosquito-borne zoonotic arbovirus, 1st identified in 1937 in uganda and called w nile bc w branch of nile. River originates in uganda: introduced to us in 1999, 1st discovered in the bronx zoo-killing valuable birds, produces 1/3 different outcomes in humans. 3rd: invades nervous system causes meningitis/encephalitis: symptoms: fever, headache, nausea, vomiting, rash, muscle weakness, swollen lymph nodes, in small # of cases, infection can result in encephalitis/meningitis, can lead to paralysis, coma, and possibly death. Spread of wnv: spread across us s am. in < 10 years by infected birds and mosquitoes, not contagious human human. # of human cases 2015: 48 states had cases in humans and birds, overall: 1732 cases of wnv in ppl reported to cdc, 65%=neuroinvasive (encephalitis, meningitis, 168 death sin us; 1/3 of cases in tx, in tx: 2015: 383 cases, 235 neuroinvasive, 4 deaths.

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