VTPB 405 Lecture Notes - Lecture 30: Hbeag, Immunoglobulin G, Dna Virus

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Hepatitis A
opicoronavirus
incidence worldwide
Fecal oral transmission
Clinical symptoms
Asymptomatic wojaundice mostly
self limited
can relapse
immunocompromised fulminant hepatitis
Lab
Acute HAV IgM NO chronic state
Past vaccinated HAV IgG
Treatment supportive Post
exposure
High risk aimmunoglobulin
travelers to endemic areas vaccine
men who have sex wmen
contam Shellfish
chronic liver disease pts
Vaccine life long immunity
inactivated
Hepatitis B
oHepadnavirus
partially double stranded circular enveloped DNA virus
parenteral Transmission
Child birth unprotected sex needle stick NDU etc
of risk for hepatocellular carcinoma
Clinical symptoms
Acute hepatitis Chronic hepatitis 120
ujaundice dark urine fever malaise nausea TIFT ALT AST
uinflammation involves lobules of liver da portal tracts
Lab
Acute HBS
Ag HBeAg AntiHBCAg 19M
Window AntiHBCAg 19M
Chronic HBS
Ag HBeAg HAntiHBcAgIgG
Resolved AntiHBCIgG AntiHBSAs IgG no viral DNA
Vaccinated AntiHBS
Ag IgG no viral DNA
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