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Lecture 12

WFSC 301 Lecture 12: Lecture 12 Malignant Edema
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1 Page
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Spring 2017

Department
Wildlife & Fisheries Sci.
Course Code
WFSC 301
Professor
Walter Cook
Lecture
12

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Lecture 12: Malignant Edema
Etiologic agent: Clostridium septicum
wound infection is quick and fatal
acute, generally fatal toxemia
Does affect all ages and most species
Spore forming
Signs:
• lethargy
Loss of appetite
• anorexia
• intoxication
fever
local lesions
death in 1 - 2 days
Host:
Cattle
Sheep
Goats
• swine
• Horses
• Poultry
NOT human Edema
Not zoonotic
Human edema causes blood vessels to release extra fluid into the tissue
Transmission and Geographic distribution
Mostly found in Australia and Brazil
Enters body through
- puncture wounds
- injuries
- castration docking
Gross Lessions
Malignant edema produces a gangrenous swelling at the sight of infection
discharge a reddish gelatinlike substance mixed with gas bubbles
putrid odor
Diagnosis
• Antemortem
- Check for clinical signs
- not very effective
• Postmortem
- Fluorescent antibody staining from tissue smear
- PCR
- used for direct identification
- Presence of lesions
Vaccination
Annual vaccination in high risk areas advised
Revaccination following severe trauma

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Description
Lecture 12: Malignant Edema Thursday, March 2, 2017 at 3▯48 PM Etiologic agent: Clostridium septicum • wound infection is quick and fatal • acute, generally fatal toxemia • Does affect all ages and most species • Spore forming Signs: • lethargy • Loss of appetite • anorexia • intoxication • fever • local lesions • death in 1 - 2 days Host: • Cattle • Sheep • Goats • swine • Horses • Poultry NOT human Edema • Not zoonotic • Human edema causes blood vessels to release extra fluid into the tissue Transmission and Geographic distribution • Mostly found in Australia and
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