BIOL 1001 Lecture Notes - Lecture 5: Homologous Chromosome, Sister Chromatids, Seminiferous Tubule

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Meiosis
1. a tetrad(bivalent) forms because of all chromosomes duplicate during Interphase I
-Then the homologous chromosomes line up
2. during meiosis I, homologous chromosomes separate
3. during meiosis II, sister chromatids separate. Meiosis I similar to mitosis
4. crossing over occurs during Meiosis I
Homologous Chromosomes
· are a pair of chromosomes that resemble eachother in size, shape, and the genes they carry
Human Chromosome Number
· diploid= 46
· haploid=23
· 23 pair of bivalents form
· ½ of each set for father. ½ from mother
· mitosis occurs in somatic cells and produces cells with 46 chromosomes-two of each type.
Random Alignment of Homologous Chromosomes During Meiosis I
· either maternal or paternal member of a homologous pair can end up at either pole of a cell
· homologues can go up or down in the previous figures
· the chromosomes in a gamete are a mix of chromosomes form the 2 parents
· our gametes almost always contain both maternal and paternal chromosomes
· all gametes normally contain only 23 chromosomes.
Possible Chromosomal Combos
· 2^n or 2^23, or 8.5 million combos
· for a cell with 8 chromosomes or 4 pairs, the haploid number is 4. The possible combos are
2^4 or 16.
· THIS IS IN THE ABSENCE OF CROSSING OVER
8 Possible Chromosome Combos
· 2n=6 and n=3
Crossing Over During Meiosis I
· each chromosome becomes zipper to its homologue
· all 4 chromatids are closely aligned and form a chiasma
· nonsister chromosomes exchange segments
· occurs during prophase I of Meiosis I **TEST QUESTION*8
Effect of Crossing Over
· each homologous chromosome contains both maternal and paternal segments
1. creates new allele combos in offspring
2. allows for genetic mixing
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Document Summary

Meiosis: a tetrad(bivalent) forms because of all chromosomes duplicate during interphase i. Then the homologous chromosomes line up: during meiosis i, homologous chromosomes separate, during meiosis ii, sister chromatids separate. Meiosis i similar to mitosis: crossing over occurs during meiosis i. Are a pair of chromosomes that resemble eachother in size, shape, and the genes they carry. Mitosis occurs in somatic cells and produces cells with 46 chromosomes-two of each type. Random alignment of homologous chromosomes during meiosis i. Either maternal or paternal member of a homologous pair can end up at either pole of a cell. Homologues can go up or down in the previous figures. The chromosomes in a gamete are a mix of chromosomes form the 2 parents. Our gametes almost always contain both maternal and paternal chromosomes. All gametes normally contain only 23 chromosomes. 2^n or 2^23, or 8. 5 million combos. For a cell with 8 chromosomes or 4 pairs, the haploid number is 4.

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