BIOL 3327 Lecture Notes - Lecture 47: Anterior Interventricular Branch Of Left Coronary Artery, Coronary Vasospasm, Coronary Artery Disease

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Chest pains when blood flow to the coronary arteries to the heart is inadequate. Ischemia: an imbalance between the demands of oxygen that the heart makes and the supply of oxygen that the heart gets (delivered by right coronary artery and left anterior descending artery) Sensation of what it feels like if you exercise really hard and feel pain in your chest; slight imbalance of oxygen in a healthy heart. Atherosclerosis: excess fatty substances that cake on the arteries, a 60-70% decrease in lumen size, damaging the endothelial cells. Coronary artery spasm: when the vascular smooth muscle (arteries) will spasm and close off blood flow. Region of myocardial necrosis (e. g. tissue damage) due to prolonged cessation of blood supply. Stable/effort angina: can be caused by stress or physical activity. If a person rests, it usually goes away. Variant angina: when corona arteries are very easy to trigger in a spasm. There tends to be polymorphisms in different ca2+ channels.

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