BIOL 221 Lecture Notes - Lecture 2: Cardiac Glycoside, Blood Pressure, Verapamil

27 views2 pages

peachbeetle258

11 Feb 2020

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

In summary, factors that increase esv include increased edv due to increased filling time or increased venous return, decreased afterload, and increased contractility due to positive inotropic agents. In summary, decreased edv due to decreased time for filling (increased heart rate or changes in rhythm) or decreased venous return, increased afterload or decreased contractility decrease stroke volume. Increased afterload is a greater pressure against which heart has to work and is due to increased mean arterial pressure. Decreased contractility would be due to negative inotropic agents. Used to treat congestive heart failure (chf), atrial arrhythmias. Heart strength can be controlled clinically by drugs such as digitalis (e. g. , digoxin) and calcium-channel blockers (e. g. , verapamil). Digitalis and other cardiac glycosides make calcium more available within the cell. They are used to treat congestive heart failure (chf) and atrial arrhythmias because they increase strength and decrease heart rate. Calcium-channel blockers inhibit calcium influx, thereby decreasing strength of contraction.

Related Questions

c) How going from laying to standing affects arterial blood pressure in the head region?

When we are laying down the Mean Arterial Pressure (MAP) is at the same level of the heart which is about 100 mm Hg. When we try to stand up from the lying position, our head is placed above our heart and gravity starts to pull the blood back downwards to our heart and feet. Return of venous blood is reduced and this leads to a decrease in cardiac stroke volume and decline in mean arterial pressure which is reduced to 60-70 mm Hg. This decreases the flow of blood to head. In response to this reduction in arterial blood pressure in the brain, parasympathetic nervous system is withdrawn and sympathetic nervous system is activated to pump more blood to head region via increased heart rates.

d) How the baroreceptors reflex explains the higher HRs during standing

When a person stands up, baroreceptor reflexes are rapidly activated to restore arterial pressure so that mean arterial pressure normally is not reduced by more than a few mmHg when a person is standing compared to lying down. However, in order to maintain this normal mean arterial pressure, the person who is standing upright has increased systemic vascular resistance (sympathetic mediated), decreased venous compliance (due to sympathetic activation of veins), decreased stroke volume (due to decreased preload), and increased heart rate (baroreceptor-mediated tachycardia).

21. Aerobic training would decrease submaximalheart rate, which is beneficial for aerobic performance because

a. it saves energy used by heart beats.

b. it gives longer time for ventricular filling.

c. a and b.

d. None of above.

22. Aerobic training would ________ anaerobicpower during maximal exercise.

a. delay onset of

b. facilitate onset of

c. rely on

23. Compared to untrainedindividuals, trained endurance athletes have

a. higher maximal heartrates.

b. higher resting cardiacoutputs.

c. higher resting heartrates.

d. higher maximal strokevolumes.

24. What is the likely outcome oflow volume, low intensity training?

a. increased aerobiccapacity

b. increased anaerobiccapacity

c. increased aerobic andanaerobic capacity

d. little improvement in eitheraerobic or anaerobic capacity

25. Which of the followingstatements explaining the increase in SV after aerobic training iscorrect?

a. reload, contractility, andafterload increase

b. preload, contractility, andafterload decrease

c. preload and contractilityincrease, afterload decreases

d. preload decreases,contractility and afterload increase

26. When motor units contract moresynchronously,

a. muscles cannot sustainsteady forces anymore

b. muscles increase the rate offorce development

c. the ability to generateforce is impeded

d. a single motor neuron nowinnervates several motor units

27. In general, whole-muscle hypertrophy in humans most likely resultsfrom

a. mostly fiberhyperplasia

b. entirely fiberhyperplasia

c. mostly fiberhypertrophy

d. equal contributions of fiberhypertrophy and fiber hyperplasia

28. Overload can be achieved by

a. increasing intensity.

b. increasing recovery time.

c. a certain type of training.

d. All of above.

29. Resistance training increases forceproduction by

a. neural adaptation followed by intramuscular adaptation.

b. intramuscular adaptation followed by neural adaptation.

c. simultaneous neural and intramuscular adaptation.

30. Training causesan increase in stroke volume due to all of the following except

a. increased filling time.

b. increased left ventricular volume.

c. increased cardiac and arterial stiffness.

d. improved intrinsic contractile function.

31. The risk of DOMS after a giventraining session can be reduced by which trainingstrategy?

a. train at high intensity withboth resistance and anaerobic training components

b. train with primarily intenseeccentric exercise

c. reduce eccentric componentof muscle action

d. employ more downhillexercise in the training program

32. After anaerobic training, thecross-sectional areas of ______ are larger than before thetraining.

a. type I fibers

b. type II fibers

c. type I and type IIfibers

33. Aerobic training would cause __________cardiac hypertrophy, which is increased ______________.

a. concentric, the diameter of left ventricle.

b. eccentric, the diameter of left ventricle.

c. concentric, the wall thickness.

d. eccentric, the diameter and wall thickness of leftventricle.

34. InFartlek training, ___________ is changed based on

olivewater-buffalo410

1. Reflexes associated with Golgitendon organs prevent skeletal muscles from

a. stretching toofar

b. contracting with too muchforce

c. accumulating too much lacticacid

d. exercising toolong

2. Why do plasma glucoseconcentrations start to decline after prolonged enduranceexercise?

a. Glucagon releasedecreases.

b. Insulin releaseincreases.

c. Cortisol releasedecreases.

d. Glycogen stores aredepleted.

3. During a graded aerobic exercise,

a. SBP gradually increases while DBP remains same or slightlydecreases.

b. SBP remains same or slightly decreases while DBP graduallyincreases.

4. Factor(s) affecting blood pressure is(are)

a. HR.

b. SV.

c. Q.

d. TPR.

e. All of above.

5. Where does waterportion of sweat come from?

a. Inside of muscle cells.

b. Urine.

c. Plasma.

6. End-diastolic volume (EDV) -end-systolic volume (ESV) =

a. cardiac output(CO).

b. mean arterial pressure(MAP).

c. stroke volume(SV).

d. ejection fraction(EF).

7. The major factor affecting blood flow is

a. viscosity ofblood.

b. length of vessel.

c. radius of vessel.

d. shear stress ofvessel.

8. Accumulation of metabolicby-products in muscle (H⁺,CO₂, heat) leads to

a. vasoconstriction.

b. vasodilation.

c. sympatheticactivation.

d. reduced muscle bloodflow.

9. During a grated exercise until the point ofventilator threshold (VT) occurring,

a. pulmonary ventilation (VE) increases proportionally to exerciseintensity increase.

b. pulmonary ventilation (VE) increases disproportionally toexercise intensity increase.

10. Immediately stopping a steady-statesubmaximal exercise, VE steeply decreases. This decrease is dueto

a. decrease in PCO₂, H⁺, and the coretemperature (metabolic effect).

b. decrease in neural input from CNS and feedback from activemuscle.

11. During the recovery period after asteady-state submaximal exercise, VE gradually decrease because

a. decrease in PCO₂, H⁺, and the coretemperature (metabolic effect).

b. decrease in neural input from CNS and feedback from activemuscle.

12. Valsalvamaneuver is dangerous because

a. sore abdominal muscles.

b. a drop in blood pressure if Valsalva maneuver iscontinued.

c. a dangerous rise in blood pressure immediately afterstarting Valsalva maneuver.

d. b and c are correct.

e. All of above are correct.

13. The point atwhich pulmonary ventilation (VE) increases disproportionately withoxygen consumption (VO₂) during graded exercise iscalled

a. ventilatory threshold (VT).

b. lactate threshold (LT).

c. anaerobic threshold (AT).

14. Which condition duringexercise induces the right shift of hemoglobin's oxygen-binding affinity curve(Bohr effect)?

a. ADP accumulation

b. lower pH

c. mechanical compression ofmuscle capillaries

d. local hypoxia(low O₂)

15. How is bloodpressure response during submaximal exercise different between armsand legs?

a. Arms have a higher.

b. Legs have a higher.

c. They are the same

d. They can't be compared

16. Which of thefollowing does not increase the heart'sstroke volume?

a. Enhanced cardiac filling and ejection

b. Neurohormonal influence

c. Training adaptations that expand blood volume

d. Training adaptations that increase resistance to bloodflow

17. Which of the following willdecrease stroke volume (SV)?

a. increased preload

b. increasedcontractility

c. increased Calcium(Ca²⁺) concentrations

d. increasedafterload

18. For two athletes with sameVO₂max, An athlete who has _____ lactate thresholdpredicts better performance.

a. higher

b. lower

c. It doesn

ochrecricket710

BIOL 221 Lecture Notes - Lecture 2: Cardiac Glycoside, Blood Pressure, Verapamil

Document Summary

Get access

Related Documents

BIOL 221 Study Guide - Final Guide: External Intercostal Muscles, Intrapleural Pressure, Thoracic Cavity

BIOL 221 Lecture Notes - Lecture 4: Myogenic Mechanism, Angiogenesis, Perfusion

BIOL 221 Lecture Notes - Lecture 4: Cardiogenic Shock, Hypovolemia, Extracellular Fluid

Related Questions