BIO 111 Lecture Notes - Lecture 22: Tunxis Community College, High-Protein Diet, Transferrin

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80% taken to bone marrow to make rbc. 70% total body iron is contained in rbc. Iron is transported in blood carried by proteins iron is dangerous free, so carried by transferrin, 80% of absorbed iron taken to bone marrow. Hemoglobin is 95% of the protein in rbc heme portion and iron portion non-heme iron must have heme. Iron stored in liver (20%) as stored ferritin. Blood levels tightly regulated (10mg/dl) - depending on age between 9-10 grams/dl (2 nickels worth) Travels free in blood or carried in blood by albumin (a blood protein that maintains oncotic pressure) Stored in the bone and other tissues and in extracellular fluids. Several factors effect urinary output increasing urinary output: caffeine diuretic, increases ca loss when intake exceeds 400mg/d, protein if unbalanced (high protein diet) increased urinary excretion, sodium consumption over 2400 mg/d increases urinary excretion of ca. Calcitronin (stimulates to reduce bc level) pee more.